Aki Light/Mega Man • Mega Mini • Suna Light • Dr. Light • Rush • Bert Wily

Robot Masters
Sgt. Night/Lord Obsidian • Namagem/Daini • Skull Man
Air Man • Blasto Woman • Chaotique • Chemistry Man • Cut Man • Drill Man • Elec Man • Fire Man • Gargantu Man • Guts Man • Turbine Man • Wave Man

Other antagonists
Dr. Wily • Hoover Gang

Supporting cast
Ashley Adderley • The Bluster Bunch • Drill Man Senior • Good Guild • Hal • Hypno Woman • Ice Man • Junk Man • Man Man • Miss CHO • Peter Punkowski • Principal 100100 • Wood Man

Throwing Shade Part I • Throwing Shade Part II • Drilling Deep • Videodrone • Please Rush Home • Blaze of Glory • Nice on Ice
Hard Times in Silicon City • Tripping the Light Fantastic • Running Wild • Unfriendly Competition • Opposites Attract
I.C.E. (In Case of Emergency) • Trust Your Guts, Man! • Drill of the Hunt • Power Cycle • Bored to be Wild
Enter the Wood Man • Lightfall Part I • Lightfall Part II • Rush to Greatness • SWISH • Minus Mini • A Cut Above
A Bot and His Dog • This Man, This Man Man • A Guilded Cage • To Air Is Robot • Watt's Happening?! • Chill Out, Bruh
Big Bad Dreams • License to Drill • All Good in the Wood • Fire Man in the Hole • A Split End • All Play and No Work
More More More! • Blast Resort • Too Much Is Never Enough • The Bluster Bunch • It’s Chemistry, Man • Flower Power • Enemy of my Enemy • Old School • This Is Not a Drill • A Man Man For All Seasons • Change the Charge • Hide And Secrets • Make The Cut • Panic in the Lighthouse • The Gauntlet Part I • The Gauntlet Part II